All You Need To Know About EGF, Epidermal Growth Factor

Epidermal Growth Factor (EGF) stands out as a remarkable ingredient that holds the key to promoting skin rejuvenation and renewal. In this journal, we'll take a deep dive into the world of EGF and discover its remarkable role in promoting youthful, radiant skin.

What is EGF? 

In the realm of skincare, EGF is harnessed for its ability to stimulate cell renewal and collagen production, making it a sought-after ingredient for achieving smoother, firmer, and more youthful skin. EGF is a type of peptide consisting of 53 amino acids, also known as ‘sh-Oligopeptide-1’, ‘rh-Oligopeptide-1’. The reason why they have different names is because they are derived from different genetic origins or mixed with other ingredients.

EGF was originally used for wound healing medicine, and it's now widely used as a raw material for cosmetics because of its functions to improve skin barrier, wrinkles and elasticity. EGF is one of the skin's growth factors, present in every individual's body. However, the quantity varies among individuals, and multiple studies indicate that EGF levels in the skin decline significantly after mid to late 20s. Therefore, prioritizing anti-aging care becomes increasingly crucial starting from the mid-20s.

How does EGF work?

EGF binds specifically to Epidermal Growth Factor Receptor (EGFR) on the cell membrane, stimulating cell growth. This activation targets keratinocytes, responsible for producing keratin in the epidermis. It fosters cell division, thus promoting both keratin growth and differentiation. Consequently, EGF effectively regenerates skin and reinforces its barrier function. Moreover, it enhances the synthesis of collagen, elastin, and hyaluronic acid by promoting fibroblast division in the dermis. This means it has anti-aging benefits, leading to improvements in wrinkles and skin elasticity.

What are the benefits of EGF?

As mentioned, EGF promotes cell renewal. As we age, the rate of cell turnover naturally slows down, leading to a dull complexion and appearance of fine lines and wrinkles. This is when EGF steps in to rejuvenate the skin by accelerating the cell turnover process, leading to a more youthful and radiant complexion.

Collagen is a vital component for maintaining skin’s elasticity and firmness. EGF stimulates fibroblasts, the cells that are responsible for producing collagen, resulting in improved skin elasticity and reduction in the appearance of sagging skin and enlarged pores. 

By promoting cell renewal and collagen production, several studies have shown that EGF improves the appearance of acne scars, promotes a more even skin complexion and minimizes inflammation.

Who can benefit from EGF?

If you experience any sign of aging in your skin, it's probably the good time to start integrating EGF into your skincare routine. If you receive some invasive skin procedures such as micro-needling or laser treatment, topical EGF skincare products will also help with healing and skin regenration. EGF’s versatility makes it suitable for all skin types including sensitive skin. Anyone with mature skin, or starting their anti-aging skincare can benefit from EGF.

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